Measurements with Interdigitated Array Microelectrodes (58k)
Thin film carbon electrodes are finally practical. Thus, one can now
seriously explore bioanalytical applications of this fascinating technology.
Yuzuru Iwasaki and Masao Morita of NTT review progress to date.
to Calculate,When to Use, andHow to Understand Curvature Measuresof
Intrinsic and parameter-effect curvatures as measures of nonlinearity
may help in evaluation of the acceptability of a particular physical
model. M. Karolczak of Adam Mickiewicz University in Poznan, Poland
discusses their significance and various aspects of their use in the
analysis of experimental data. The relationships of quantitative measures
of nonlinearity to Studentís t-values, parametersí correlation coefficients,
confidence intervals, and model choice are indicated.
Electrophoresis/ Electrochemistry (58k)
separation techniques show great promise for bioanalytical chemistry.
Their high plate count and compatibility with small volume samples are
intriguing for microdialysates. Thomas J. OShea of Searle and
Susan Lunte of Kansas University review the use of electrochemical detection
for capillary electrophoresis.
Determination of Trace Concentrations of Metals in the Environment
spectroscopy dominates trace metal determinations in the environment.
Nevertheless, electroanalytical chemistry is also used and should especially
be considered for toxic heavy metals. Adrian Bott continues his educational
series on electrochemistry.
Monitoring of Subcutaneous Glucose and Lactate Using Microdialysis with
On-Line Enzyme Electrodes (73k)
is a continuous sampling technique. It is appropriate to consider whether
some substances can be continuously sensed in the dialysate stream.
This is a progress report for an ongoing project at BAS and E. Heller