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Simultaneous
Determination of Caffeine from Blood, Brain and Muscle Using Microdialysis
in an Awake Rat and the Effect of Caffeine on Rat Activity (202k)
Kathleen Heppert and Malonne Davies of BAS Kansas demonstrate delivery
and monitoring of caffeine in an awake, freely moving rat and discuss
determination of caffeine levels using microdialysis probes.
Characterization
of Chemical Reactions Coupled to Electron Transfer Reactions Using Cyclic
Voltammetry (143k)
Adrian W. Bott of Bioanalytical Systems, Inc. discusses the use of cyclic
voltammetry for mechanistic studies of systems in which electron transfer
reactions are coupled with chemical reactions and the characteristic
appearance of cyclic voltammograms associated with different mechanisms.
Simultaneous
Determination of Six Protease/Reverse Transcriptase Inhibitors in Human
Plasma Utilizing LC/MS/MS (348k)
Ronald
E. Shoup, Xiaoli Ren, Angela P. Johnson, Donald A. Gray, Simone Evarts,
Lynn Gill and Brian D. Beato of BAS Analytics describe their single
method for profiling six protease/reverse transcriptase inhibitors in
human plasma for use in combination therapy research and in screening
potential clinical trial subjects.
Serotonin’s
Role in Alcohol’s Effects on the Brain (48k)
David
M. Lovinger of Vanderbilt University School of Medicine describes the
neurotransmitter serotonin’s actions in alcohol’s effects on the brain
and alcohol abuse.
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