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Vol. 20 No. 1
Bioanalytical Systems, Inc. / June 2002


Foreword (27k)
We have focused this issue on neuroscience, particularly neurochemistry...

Analyzing Analytical Outsourcing (62k)
Article by Pete Kissinger of BAS, reprinted with permission from March 2000 Contract Pharma.

Increased Assay Robustness and Throughput Using Automated 96-Well Solid Phase Extraction
Sheela Das, Ellen Fisher, Tim Grever, Bruce Burras and Helene Freiser discuss an automated method using the 96-well solid phase extraction format on a TomTec Quadra 96.

Feasibility of Ion-Pair Reversed-Phase LC/EC Detection for Determination of Acetylcholine in Microdialysates Collected Without Acetylcholinesterase Inhibitors (105k)
Hidekazu Sotoyama, Yongxin Zhu, James Gitzen, Fuming Xie and Peter T. Kissinger explain how acetylcholine (ACh) concentration in medial prefrontal cortex (mPFC) was determined using in vivo microdialysis and LC/EC without acetylcholinesterase (AChE) inhibitors in awake and freely moving rats.

Behavioral “Spectoscopy” with the Force-Plate Actometer (209k)
Prof. Stephen Fowler, of Kansas University, describes a unique approach to detect subtle effects often not measurable with standard methodology.

Simplification of Necropsy Observation in the Pharmaceutical Industry (51k)
James H. McGee discusses findings from veterinary clinical pathology and necropsy examinations.

Tools and Services for CNS Research From BAS (215k)
Adrian Bott and Scott Glazier discuss products and services for neuroscience available from BAS.

Products, Literature, Miscellany (264k)
Products: Culex® Automated Blood Sampler; Chads for Vials™ labeling system; New brain microdialysis probes for use in rodents.
In the LC Literature: Bruce Solomon discusses Homocysteine by Capillary Electrophoresis, and Microchip Capillary Electrophoresis.
In the EC Literature: Reviewed by Adrian Bott and Jeff Turner.
In the In Vivo Literature: Reviewed by Chandrani Gunaratna, Tianyi Zhang and Jean Zhou.
Miscellany: Workshops, Symposia, Conferences, BAS remembers Martine Brettnacher and M.J. Weaver.
BAS People: Profiles of Sheela Das and Andy Brown.


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